This session will explore the unique medical, psychosocial, and systems-level considerations impacting both older adults and pediatric populations living with HIV. Participants will gain insight into emerging trends across the lifespan, including perinatal transmission, pediatric treatment and transition to adult care, aging-related comorbidities, and long-term HIV management. The session will also highlight best practices in age-responsive and family-centered HIV care, along with strategies to support health, stability, and quality of life from childhood through older adulthood.